Cosmetic Grade Azelaic Acid-CAS 123-99-9
Product Name: Azelaic Acid
Abbreviation: AZA
INCI Name: Azelaic Acid
CAS No.: 123-99-9
Grade: Cosmetic Premium Grade (High-purity Acne & Redness Repair Special)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Uniform Fineness, No Caking, Slight Characteristic Odor, High Purity Texture
Molecular Formula: C₉H₁₆O₄
Molecular Weight: 188.22
MOQ (Minimum Order Quantity): 25KG
Solubility: Slightly soluble in water, easily soluble in hot water and alcohol solvents; good compatibility with oil-phase and emulsion systems, stable in weak acid and neutral formulas, uniform dispersion after heating and dissolving, suitable for acne gel, cream and lotion production
Core Efficacy: Efficient anti-acne and anti-inflammation, inhibit propionibacterium acnes, control skin sebum secretion, unclog pores, gently exfoliate, fade inflammatory red marks and post-acne pigmentation, brighten dull skin, improve rough and oily skin texture
Key Characteristics: Classic safe skin-clearing active ingredient, dual efficacy of treating acne and repairing red marks; milder than salicylic acid and tretinoin, low irritation, non-photosensitive, available for daytime use; inhibits melanin hyperactivity while anti-inflammatory, improves uneven skin tone, suitable for oily, acne-prone and sensitive acne skin
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and agglomeration
Shelf Life: 24 Months
Application: Widely used in anti-acne essence, acne repair gel, oil-control lotion, red mark fading cream, gentle exfoliating skincare, oily skin conditioning and sensitive acne skin functional cosmetic formulas
Azelaic Acid, Cosmetic Grade Azelaic Acid, 99% Azelaic Acid, Anti-acne, Oil Control, Anti-inflammatory, Fade Red Marks, Skin Brightening, Gentle Exfoliating, Skincare Raw Material
Cosmetic Grade Azelaic Acid-CAS 123-99-9
Cosmetic Grade Azelaic Acid is a natural straight-chain dicarboxylic acid, a gold-standard mild skin-clearing active ingredient for acne and red mark repair in the skincare industry.
Different from high-irritation exfoliating and anti-acne ingredients, 99% high-purity azelaic acid achieves efficient skin conditioning with low skin burden, solving the common pain points of acne skin such as repeated acne, inflammatory redness, post-acne dark marks, oily dullness and rough pores.
It can precisely inhibit the activity of Propionibacterium acnes, cut off the bacterial growth environment, effectively improve inflammatory acne, closed comedones and pustules, and reduce acne recurrence. By regulating sebaceous gland secretion, it controls excessive oil production, balances skin water and oil, and refreshes oily and sticky skin.
In terms of skin repair and brightening, azelaic acid can inhibit the abnormal proliferation and activity of melanocytes, reduce local pigment deposition caused by inflammation, fade fresh red marks and old dark acne marks, and uniformly brighten skin tone.
With mild exfoliating power, it can accelerate the metabolism of aged keratin, unclog blocked pores, improve rough and dull skin texture, and refine enlarged pores. It has no photosensitive risk, safe for daytime long-term use, low irritation, and compatible with sensitive acne-prone skin. It is an indispensable core raw material for building safe, mild and efficient acne repair and skin conditioning skincare systems.



Key Benefits
• Dual Anti-acne Mechanism, Inhibit Acne Recurrence: Target Propionibacterium acnes, block bacterial metabolism and reproduction, improve inflammatory acne and closed comedones; regulate oil secretion, keep pores unclogged, and fundamentally reduce acne repeated growth.
• Anti-inflammatory & Fade Marks, Repair Acne Skin: Effectively relieve skin inflammatory redness, soothe acne swelling and sensitivity; inhibit melanin activity in inflammatory areas, fade red marks and dark pigmentation, and restore uniform skin tone.
• Mild Exfoliation, Refine Pore Texture: Gentle keratin metabolism power, avoid strong irritation of high-concentration acid products; accelerate waste keratin shedding, improve rough dull skin, refine enlarged pores, and make skin smooth and delicate.
• Non-photosensitive & All-day Available: No photosensitive risk, different from salicylic acid and retinol which are limited to night use; support daytime continuous oil control and acne repair, prevent light-induced inflammation and pigmentation.
• Low Irritation & Sensitive Acne Skin Friendly: Milder than salicylic acid, glycolic acid and tretinoin, low skin irritation, no easy peeling or stinging, suitable for oily acne skin and sensitive fragile acne skin.
• Stable Formula & Easy Mass Production: High-purity raw material with stable chemical properties, good dispersion in emulsion and gel systems, not easy to discolor and deteriorate, simple formula debugging, high yield rate for industrial production.
Applications
• Professional Anti-acne Essence & Serum: Core active ingredient of targeted acne essence, efficiently improve inflammatory acne, pustules and closed comedones, control oil and reduce acne swelling.
• Acne Repair Gel & Lotion: Suitable for mild and refreshing acne gel and oil-control lotion formulas, balance skin oil, soothe skin inflammation, and maintain stable acne skin state.
• Post-acne Red Mark & Pigment Fading Cream: Added in acne mark repair cream and skin brightening cream, fade inflammatory red marks and old dark acne marks, improve uneven skin tone.
• Gentle Exfoliating & Pore Refining Products: Applied in keratin conditioning and pore refining skincare, gently exfoliate, improve rough and dull skin, and restore delicate and smooth skin texture.
• Oily Skin Daily Conditioning Series: Used in long-term oil-control and skin-balancing skincare products, improve oily shine, rough pores and recurrent acne problems of oily skin.
• Sensitive Acne Skin Repair Products: Build low-irritation professional acne repair system for sensitive acne-prone skin, avoid excessive irritation and barrier damage, and safely improve problematic skin.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Azelaic Acid | Compliant |
CAS No. | 123-99-9 | Compliant |
Appearance | White Fine Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.62% |
Melting Point | 106℃~109℃ | 107.2℃ |
Loss on Drying | ≤0.5% | 0.12% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Azelaic Acid?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and acne repair efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 5%-10% for daily oil-control and mild acne skincare; 10%-15% for high-efficiency anti-acne and red mark fading essence and cream, adjustable according to product efficacy positioning.
• Q4: What is the difference between Azelaic Acid and Salicylic Acid?
A4: Salicylic acid has strong exfoliating penetration but high irritation and photosensitivity, only suitable for night use. Azelaic acid is milder, non-photosensitive, available all day, has dual effects of anti-inflammation and fading marks, and is more suitable for sensitive acne skin long-term conditioning.
• Q5: Is Azelaic Acid irritating to sensitive skin?
A5: Low irritation and high safety. Compared with fruit acid and salicylic acid, azelaic acid has milder skin-friendliness, will not cause severe peeling or stinging, and can be used safely for sensitive acne-prone skin with reasonable dosage control.
• Q6: What ingredients is Azelaic Acid suitable for compounding?
A6: It can be perfectly compounded with nicotinamide, panthenol, centella asiatica extract and hyaluronic acid, realizing anti-acne, anti-inflammation, soothing repair and brightening synergistic effects, optimizing product skin-friendliness and efficacy.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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